Insulin is a biologic compound that can be difficult and expensive to produce. Drugs in Tier 1 and 2, mainly lower-priced generics and “preferred brand-name” drugs, have lower co-pays than more expensive “nonpreferred brands” in Tier 3 or 4. Here’s why, and why it isn’t necessarily a bad thing. Why Is Insulin So Expensive? Here's the real reason health care costs so much more in the US Published Thu, Mar 22 2018 11:37 AM EDT Updated Mon, Sep 3 2018 11:08 AM EDT Yoni Blumberg @YoniBlum So why are Canada Goose jackets so expensive? There are several reasons it's become increasingly expensive – … High-end phones from Apple, Samsung, Google, and others can now cost hundreds of dollars more than they did just a couple of years ago. The City of Cholula . The taste didn't disappoint at all, but it was so weak I ended up using it more like a ketchup than a hot sauce. Here's why many prescription drugs in the US cost so much—and it's not innovation or improvement Published Mon, Jan 14 2019 11:17 AM EST Updated Mon, Jan 14 2019 11:24 AM EST Yoni Blumberg @YoniBlum This is why it's been more expensive to update your home lately The cost of lumber rose to historic highs in the summer, before cooling off some. Experts don’t know exactly why hearing aids are still so costly, except that companies continue to invest in improvements, and fees usually cover the services of a highly trained audiologist. Cholula was home to an estimated 100,000 people and was known for a bustling market and for producing excellent trade goods, including pottery. The fresh peppers are mashed, mixed with a small amount of Avery Island salt extracted from the salt mines that lie beneath the Island, and placed in oak barrels. 2018 Nov;78(17):1777-1781. doi: 10.1007/s40265-018-1009-0. Part of the appeal is that the down-filled jackets are very high quality and keep people warm. Cholula is barely a hot sauce I bought a bottle of Cholula original because I heard it was really tasty. In 1519, Cholula was one of the most important cities in the Aztec Empire. Located not far from the Aztec capital of Tenochtitlan, it was clearly within the sphere of Aztec influence. Why Biologics and Biosimilars Remain So Expensive: Despite Two Wins for Biosimilars, the Supreme Court's Recent Rulings do not Solve Fundamental Barriers to Competition Drugs .